salvinorin a for sale. Many readers of The Entheogen Review will be familiar with the largest legal psychedelic Salvia divinorum, an ethnomedicinal sage originally used by the Mazatec Indians of Oaxaca, Mexico. This plant’s active compound is the most potent naturally occurring psychedelic known, producing clear effects at doses of one milligram or less when vaporized (Siebert 1994). It acts at the kappa opioid receptor, and since most previously known potent opioids have been alkaloids, not diterpenoids, this discovery has excited scientists considerably. In recent years, over a hundred derivatives of salvinorin A have been synthesized in hopes of producing new medicines. A few of these derivatives have had interesting properties, but most are simply disappointing, less-potent imitations of salvinorin A itself. Other salvinorins and related compounds have also been extracted from the plant, but again, these compounds are less potent at opioid receptors than salvinorin A.
Our attention was therefore caught by a report of a derivative that was actually more potent: salvinorin B methoxymethyl ether. This in vitro result was later confirmed in mice studies, which also showed that the drug appeared to last longer than salvinorin A. Then came another report that a slight modification to this compound made an even stronger drug, salvinorin B ethoxymethyl ether, which appeared to be about ten times as potent as salvinorin A in vitro. If this turned out to be true in humans as well, it would make salvinorin B ethoxymethyl ether (henceforth referred to as “Symmetry”) one of the most potent known psychedelics, comparable to the legendary LSD. Now thoroughly intrigued, we decided to find out for ourselves. salvinorin a for sale at globaldispendsary.com